Translation

By Sajaratul Syifaa'

Statement	True / False
1. All glycoproteins are first synthesized by free ribosomes.	True
2. A cell controls the quality of ER-made proteins by targeting the mis-folded proteins to lysosome for degradation.	False
3. Cleavage of signal peptide sequence is an essential step for protein synthesis to resume in ER.	False
4. Proteins that contain internal sorting sequences retain the signals as a part of their final protein conformation.	True
5. Operon is a universal gene unit.	False
6. All RNA polymerases can bind promoter by itself.	False
7. Eukaryotic RNA polymerase II can not bind promoter by itself.	True
8. Prokaryotic RNA polymerase can not bind promoter by itself.	False
9. The bacteria culture that contains DNA fragments from a eukaryotic organism, which has been digested with a restriction enzyme and cloned into a lambda vector is known as cDNA library.	False
10. The Southern technique involves the detection of DNA fragments on membrane using a radioactive RNA probe.	True
11. One of the most significant discoveries that allows the development of recombinant DNA technology is the discovery of antibiotics used for selecting transformed bacteria.	False
12. The sequence for protein synthesis is translation, then transcription.	False
13. The products of protein synthesis are exclusively enzymes and enzyme products.	False
14. Translation is characterized by the blueprint of the RNA molecule used to bind amino acids together to form proteins	True
15. Transcription occurs in the nucleus and translation occurs in the cytoplasm.	True
16. Translation is characterized by the binding of enzymes to their substrates to produce products	False
17. For every RNA produced, there is an enzyme or enzyme product produced	False
18. tRNA are able to carry a specific amino acid and to recognize the codon for that amino acid	True
19. Translation is the synthesis of protein form the mRNA	True
20. Translation is stopped when the stop codon present at the A and P site	True
21. The first amino acid enter the A site	False
22. The codon of tRNA is complementary to the anticodon of mRNA	False
23. As the ribosome shifts down the mRNA by a distance of three nucleotides the tRNA that was in the P site moves into the E site	True
24. Translation begins when the messenger RNA bind to ribosome	True
25. The complementary matching of three nucleotides on the transfer RNA called codon and   the three nucleotides on the messenger RNA called anticodon	False