1.
Decreased binding of histone
results in the disruption of nucleosomal structure and physical accessibility
of DNA transcription.
2.
Alternative splicing occurs by
altering the patterns of exons from a single primary transcript.
3.
Gene promoter sequences which are
required for the initiation of transcription are located downstream of the
gene.
4.
Operons regulate the expression of
genes in bacteria by induction and repression.
5.
Repressor binds to the region of
operon and blocks the binding of RNA polymerase to the promoter.
6.
Amplification of gene is involved
in the development of tumours, development of drug resistance and synthesis of
ribosomal genes.
7.
Regulation of gene expression in
eukaryotes occurs at transcriptional, post-transcriptional, translational and
post-translational levels.
8.
Degeneracy of the genetic code
refers to the fact that
a)codons do not overlap
b) there are more codons than amino acids
c)code is not universal
d)the genetic code is not always a triplet code
9. Alternative splicing
a)
allows synthesis of functionally distinct proteins from the primary transcript
of a single gene.
b) occurs by altering the
patterns of exons from a single primary transcript.
c) occurs during a particular
stage during the development of different cell types.
10. The regulatory
genes in lactose operon
a)lie
adjacent to the operon and controls its function
b) are
located adjacent but outside the operon
c)
produce proteins called repressors.
11. Gene regulatory DNA sequences
a) are
also known as the enhancer and silencer sequences
b) bind
to transcription factors that link RNA polymerase II to the promoter to form
transcription-initiation complex.
c) bind
to DNA binding molecules to result in either induction or repression of
transcription.
d) are
either present upstream or downstream of the structural gene.
12. Transcription
factors
a)are
proteins that recognize and bind to specific sequences in DNA.
b) are
transcriptional units containing clusters of genes comprising regulatory gene
and protein encoding genes.
c) are
present in either the major or minor groove of the DNA helix.
d) include general transcriptional factors and
tissue-specific transcriptional factors.
1. (TRUE) 2. (TRUE) 3. (FALSE) 4. (TRUE) 5. (TRUE) 6. (TRUE) 7. (TRUE)
8. (a) (FALSE)
(b) (TRUE) (c) (FALSE)
(d) (FALSE)
9. (a) (TRUE) (b) (TRUE) (c) (FALSE)
10. (a) (TRUE) (b) (TRUE) (c) (TRUE)
11. (a) (TRUE) (b) (FALSE) (c) (TRUE) (d) (TRUE)
12. (a) (TRUE) (b) (FALSE) (c) (TRUE) (d)(TRUE)
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