1)
Inherited
skeletal muscle disorder
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a)
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Duchenne muscular dystrophy (DMD) & Becker muscular
dystrophy (BMD) are caused by mutation in dystrophin gene
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b)
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BMD is more common and more severe than DMD
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c)
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Congenital myopathies are homogenous group of inherited
disease and occur in early childhood stage
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d)
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Genetic disorders of skeletal muscle include congenital
myopathies, congenital muscular dystrophies and muscular dystrophies
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e)
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The hallmarks of BMD are myofiber necrosis and regeneration
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2)
Clinical features of DMD and
BMD
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a)
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Clumsiness and muscle
weakness are the main symptoms of DMD
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b)
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Pseudohyperthrophy, the enlargement of calf muscle
indicates DMD
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c)
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The progression of BMD
is rapid and more fatal
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d)
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During degeneration of myofibrils,
smooth muscle tissues replace the increasing part of muscles
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e)
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BMD onset in late
childhood or aldolescence
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3)
Liposarcoma is
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a)
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Commonly occur in
children
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b)
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Arises from subcutaneous
tissue
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c)
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Well-differentiated
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d)
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Pleomorphic variants and
tend to metastasize to lungs
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e)
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Fatty differentiation,
lipoblasts are absent
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4)
Myasthenia gravis
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a)
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Can be transferred from
the infected person to animal via airborne
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b)
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Is associated with
thymic hyperplasia and thymoma
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c)
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Can be treated using
immunosuppresion, plasmapheresis and cholinesterase inhibitory drug
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d)
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Diplopia(double vision)
is due to weakness of extraocular muscle
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e)
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Thymectomy treatment can
be applied in the absent of thymic lesions
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5)
Leiomyoma
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a)
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Leiomyoma or fibroid is most
common benign tumour in testes in male
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b)
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Is composed of elongated
nuclei and spindle cells intersecting each other at right angles
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c)
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Large leiomyoma may
produce sensation
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d)
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The risk of malignancy
is higher in the present of multiple lesions
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e)
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Can be detected by the
present of menorrhagia or in the absent of metrorrhagia
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ANSWER:
1)
a) T b)F c)F d)T e)T
2)
a) T b)T c)F d)F e)T
3)
a) F b)F c)T d)T e)F
4)
a) F b)T c)T d)T e)F
5)
a) F b)T c)T d)F e)T
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